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Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium.

<h4>Background</h4>Gene therapy mediated by synthetic vectors may provide opportunities for new treatments for cystic fibrosis (CF) via aerosolisation. Vectors for CF must transfect the airway epithelium efficiently and not cause inflammation so they are suitable for repeated dosing. The inhaled aer...

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Asıl Yazarlar: Maria D I Manunta, Robin J McAnulty, Aristides D Tagalakis, Stephen E Bottoms, Frederick Campbell, Helen C Hailes, Alethea B Tabor, Geoffrey J Laurent, Christopher O'Callaghan, Stephen L Hart
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2011-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0026768&type=printable
Etiketler: Etiketle
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