Tutorial on Causal Mediation Analysis for Pharmacometricians
ABSTRACT Mediation analyses can support biomarker development by quantifying the part of the total treatment effect on clinical outcome that is mediated by the biomarker. Given that pharmacometricians are often involved in the analysis of biomarker data with pharmacokinetic–pharmacodynamic (PK–PD) m...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2026-02-01
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| coleção: | CPT: Pharmacometrics & Systems Pharmacology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/psp4.70193 |
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