Tutorial on Causal Mediation Analysis for Pharmacometricians
ABSTRACT Mediation analyses can support biomarker development by quantifying the part of the total treatment effect on clinical outcome that is mediated by the biomarker. Given that pharmacometricians are often involved in the analysis of biomarker data with pharmacokinetic–pharmacodynamic (PK–PD) m...
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| Автори: | , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Wiley
2026-02-01
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| Серія: | CPT: Pharmacometrics & Systems Pharmacology |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1002/psp4.70193 |
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