Corosolic acid ameliorates vascular remodeling in pulmonary arterial hypertension via the downregulation of STAT3 signaling

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease that is characterized by vascular remodeling of the pulmonary artery. PAH remodeling is primarily caused by the excessive proliferation of pulmonary arterial smooth muscle cells (PASMCs). Therefore, an inhibitory mechanism is e...

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Bibliografische Detailangaben

Hauptverfasser:	Akiko Kawade, Aya Yamamura, Rubii Kondo, Yoshiaki Suzuki, Hisao Yamamura
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-02-01
Schriftenreihe:	Journal of Pharmacological Sciences
Schlagworte:	Pulmonary hypertension Corosolic acid Pulmonary artery Smooth muscle Signal transducer and activator of transcription 3
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1347861322000950
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