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There and turn back again: the application of phage serine integrases in eukaryotic systems

Serine integrases (Ints) have gained prominence and have been extensively used in Synthetic Biology due to their ability to modify DNA sequences. Ints are recombinases encoded by the phage genome and have been used to unidirectionally catalyze an insertion, excision, or inversion of a specific DNA s...

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Bibliografiske detaljer
Principais autores: Thais Torquato Sales, Marco Antônio de Oliveira, Lilian Hasegawa Florentino, Rayane Nunes Lima, Elibio Rech
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-02-01
Serier:Frontiers in Bioengineering and Biotechnology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1478413/full
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