Immunoreactivity of humanized single-chain variable fragment against its functional epitope on domain 1 of CD147

Abstract Domain 1 of CD147 participates in matrix metalloproteinase (MMP) production and is a candidate for targeted therapy to prevent cancer invasion and metastasis. A functional mouse anti-CD147 monoclonal antibody, M6-1B9, was found to recognize domain 1 of CD147, and its respective mouse single...

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Autors principals:	Nutjeera Intasai, Kuntalee Rangnoi, Montarop Yamabhai, Thanathat Pamonsupornwichit, Weeraya Thongkum, Umpa Yasamut, Koollawat Chupradit, Nuchjira Takheaw, Piyarat Nimmanpipug, Chatchai Tayapiwatana
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2022-04-01
Col·lecció:	Scientific Reports
Accés en línia:	https://doi.org/10.1038/s41598-022-10657-3
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