Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection.
The regulation of proviral latency is a central problem in retrovirology. We postulate that the genomic integration site of human T lymphotropic virus type 1 (HTLV-1) determines the pattern of expression of the provirus, which in turn determines the abundance and pathogenic potential of infected T c...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2013-03-01
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| Schriftenreihe: | PLoS Pathogens |
| Online-Zugang: | https://doi.org/10.1371/journal.ppat.1003271 |
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