T Cell Receptor Vβ Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells.

There is growing evidence that CD8+ cytotoxic T lymphocyte (CTL) responses can contribute to long-term remission of many malignancies. The etiological agent of adult T-cell leukemia/lymphoma (ATL), human T lymphotropic virus type-1 (HTLV-1), contains highly immunogenic CTL epitopes, but ATL patients...

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Auteurs principaux:	Aileen G Rowan, Aviva Witkover, Anat Melamed, Yuetsu Tanaka, Lucy B M Cook, Paul Fields, Graham P Taylor, Charles R M Bangham
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2016-11-01
Collection:	PLoS Pathogens
Accès en ligne:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006030&type=printable
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