Comprehensive analyses of single-cell and bulk RNA-seq reveal the biological and prognostic roles of BMP4 in pancreatic adenocarcinoma

Bone Morphogenetic Protein 4 (BMP4) plays a critical role in development, but its function in pancreatic adenocarcinoma (PAAD) is not well understood. We found that BMP4 is minimally expressed in the normal pancreas but markedly upregulated in PAAD, correlating with poor patient survival. Pan-cancer...

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Bibliografische gegevens

Hoofdauteurs:	Ao Wang, Xinglong Shen, Shan Lu, Chao Bi, Yang Cao, Yunfeng Liu, Meng Li, Yun Zhao, Huaizhang Jin, Xiaopeng Shen, Wei Dai, Yang Lei
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2025-10-01
Reeks:	Frontiers in Molecular Biosciences
Onderwerpen:	BMP4 PAAD pan-cancer analysis ScRNA-seq prognosis
Online toegang:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1686938/full
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