Sulfated Hexasaccharides Attenuate Metastasis by Inhibition of P-selectin and Heparanase
Development of compounds that target both heparanase and selectins is emerging as a promising approach for cancer therapy. Selectins are vascular cell adhesion molecules that mediate tumor cell interactions with platelets, leukocytes, and the vascular endothelium. Heparanase is an endoglycosidase th...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2011-05-01
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| Edice: | Neoplasia: An International Journal for Oncology Research |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S147655861180062X |
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