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Predicting breast cancer prognosis using PR and PIK3CA biomarkers: a comparative analysis of diagnostic groups

Abstract Purpose To evaluate the prognostic significance of progesterone receptor (PR) expression and the PIK3CA mutation status in HR+/HER2 − breast cancer patients, with the goal of screening patients who may derive the greatest benefit from PI3K-targeted therapy. Methods A retrospective analysis...

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Autors principals: Yuting Feng, Qingzhen Song, Lei Yan, Ruoqi Li, Mengqin Yang, Peng Bu, Jing Lian
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-01-01
Col·lecció:BMC Cancer
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Accés en línia:https://doi.org/10.1186/s12885-025-13449-w
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