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Predicting breast cancer prognosis using PR and PIK3CA biomarkers: a comparative analysis of diagnostic groups

Abstract Purpose To evaluate the prognostic significance of progesterone receptor (PR) expression and the PIK3CA mutation status in HR+/HER2 − breast cancer patients, with the goal of screening patients who may derive the greatest benefit from PI3K-targeted therapy. Methods A retrospective analysis...

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Principais autores: Yuting Feng, Qingzhen Song, Lei Yan, Ruoqi Li, Mengqin Yang, Peng Bu, Jing Lian
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-01-01
Serier:BMC Cancer
Fag:
Breast cancer
Prognosis
PR
PIK3CA
Personalized treatment
Online adgang:https://doi.org/10.1186/s12885-025-13449-w
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