Pro106Leu MPL mutation is associated with thrombocytosis and a low risk of thrombosis, splenomegaly and marrow fibrosis

The P106L mutation in the human myeloproliferative leukemia virus oncogene (MPL) was shown to be associated with hereditary thrombocythemia in Arabs. The clinical and bone marrow (BM) features of P106L mutation are unknown. Genetic databases at two tertiary hospitals in Saudi Arabia were searched to...

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Detalhes bibliográficos

Principais autores:	Musa Alzahrani, Saeed Al Turki, Waleed Al Rajban, Fatimah Alshalati, Fahad Almodaihsh, Khadega A. Abuelgasim, Bader Alahmari, Thamer Al Bogami, Osama Ali, Talal Al Harbi, Mohammed A. AlBalwi, Maram Alotaibi, Aamer Aleem, Ahmed Al Asker, Areej Al Mugairi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2022-11-01
Colecção:	Platelets
Assuntos:	familial thrombocythemia hereditary thrombocytosis mpl
Acesso em linha:	http://dx.doi.org/10.1080/09537104.2022.2091773
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