C-Mannosyl tryptophan is a novel biomarker for thrombocytosis of myeloproliferative neoplasms

Abstract C-Mannosyl tryptophan (CMW), a unique glycosylated amino acid, is considered to be produced by degradation of C-mannosylated proteins in living organism. Although protein C-mannosylation is involved in the folding and secretion of substrate proteins, the pathophysiological function in the h...

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Détails bibliographiques

Auteurs principaux:	Shotaro Tabata, Yusuke Yamashita, Yoko Inai, Shuhei Morita, Hideki Kosako, Tomoyuki Takagi, Kotaro Shide, Shino Manabe, Taka-aki Matsuoka, Kazuya Shimoda, Takashi Sonoki, Yoshito Ihara, Shinobu Tamura
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2024-08-01
Collection:	Scientific Reports
Sujets:	C-Mannosylation C-Mannosyl tryptophan Thrombocytosis of myeloproliferative neoplasms Essential thrombocythemia Prefibrotic primary myelofibrosis Post-essential thrombocythemia myelofibrosis
Accès en ligne:	https://doi.org/10.1038/s41598-024-69496-z
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