Optimization of levan biosynthesis from Bacillus siamensis using batch and continuous stirred-tank bioreactors: A response surface methodology approach

Levan, a promising fructan polysaccharide for biopharmaceuticals, has limited large-scale production studies. This research optimized and scaled up levan biosynthesis from Bacillus siamensis in continuous stirred-tank bioreactors based on response surface methodology (RSM). Batch cultures optimized...

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Библиографические подробности

Главные авторы:	Pongtorn Phengnoi, Nuttinee Teerakulkittipong, Kosin Teeparuksapun, Gary Antonio Lirio, Witawat Jangiam
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-09-01
Серии:	Biotechnology Reports
Предметы:	Levan Bacillus siamensis Bioreactor Response surface methodology Continuous stirred tank bioreactor
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2215017X25000359
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