Optimization of levan biosynthesis from Bacillus siamensis using batch and continuous stirred-tank bioreactors: A response surface methodology approach

Levan, a promising fructan polysaccharide for biopharmaceuticals, has limited large-scale production studies. This research optimized and scaled up levan biosynthesis from Bacillus siamensis in continuous stirred-tank bioreactors based on response surface methodology (RSM). Batch cultures optimized...

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Autors principals:	Pongtorn Phengnoi, Nuttinee Teerakulkittipong, Kosin Teeparuksapun, Gary Antonio Lirio, Witawat Jangiam
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-09-01
Col·lecció:	Biotechnology Reports
Matèries:	Levan Bacillus siamensis Bioreactor Response surface methodology Continuous stirred tank bioreactor
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2215017X25000359
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