Computational Prediction of Phosphoinositide Binding to Hyperpolarization-Activated Cyclic-Nucleotide Gated Channels

Protein-lipid interactions are key regulators of ion channel function. Numerous ion channels, including hyperpolarization-activated cyclic-nucleotide gated (HCN) channels have been shown to be regulated by phosphoinositides (PIPs), with important implications in cardiac and neuronal function. Specif...

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Autors principals:	Ainara Claveras Cabezudo, Asma Feriel Khoualdi, Nazzareno D’Avanzo
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-03-01
Col·lecció:	Frontiers in Physiology
Matèries:	HCN channel phosphoinositides ion channel lipids protein-lipid interactions computational docking
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphys.2022.859087/full
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