Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy

Hyperpolarization-activated cyclic nucleotide-gated (HCN1–4) channels play an important role in the regulation of neuronal rhythmicity. In the present study we describe the mutation analysis of HCN1 and HCN2 in 84 unrelated patients with idiopathic generalized epilepsy (IGE). Several functional vari...

Descripció completa

Dades bibliogràfiques

Autors principals:	Bin Tang, Thomas Sander, Kimberley B. Craven, Anne Hempelmann, Andrew Escayg
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2008-01-01
Col·lecció:	Neurobiology of Disease
Matèries:	Hyperpolarization-activated cyclic nucleotide-gated channel HCN1 HCN2 Idiopathic generalized epilepsy IGE Mutation analysis
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0969996107001854
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!