ATP-binding cassette transporter expression is widely dysregulated in frontotemporal dementia with TDP-43 inclusions

The human brain is highly enriched in lipids and increasing evidence indicates that dysregulation of lipids in the brain is associated with neurodegeneration. ATP-binding cassette subfamily A (ABCA) transporters control the movement of lipids across cellular membranes and are implicated in a number...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jared S. Katzeff, Hiu Chuen Lok, Surabhi Bhatia, YuHong Fu, Glenda M. Halliday, Woojin Scott Kim
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-11-01
Schriftenreihe:	Frontiers in Molecular Neuroscience
Schlagworte:	frontotemporal dementia ATP-binding cassette subfamily A ABCA transporters lipids TDP-43 neurodegeneration
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.1043127/full
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