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Nonpromoter methylation of the CDKN2A gene with active transcription is associated with improved locoregional control in laryngeal squamous cell carcinoma

Abstract We previously reported a novel association between CDKN2A nonpromoter methylation and transcription (ARF/INK4a) in human papillomavirus associated oropharyngeal tumors. In this study we assessed whether nonpromoter CDKN2A methylation in laryngeal squamous cell carcinomas (LXSCC) conferred a...

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Principais autores: Miriam M. Ben‐Dayan, Thomas J. Ow, Thomas J. Belbin, Joshua Wetzler, Richard V. Smith, Geoffrey Childs, Brenda Diergaarde, D. Neil Hayes, Jennifer R. Grandis, Michael B. Prystowsky, Nicolas F. Schlecht
格式: Artigo
語言:Inglês
出版: Wiley 2017-02-01
叢編:Cancer Medicine
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在線閱讀:https://doi.org/10.1002/cam4.961
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