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Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods

Abstract Human endocrine cell differentiation and islet morphogenesis play critical roles in determining islet cell mass and function, but the events and timeline of these processes are incompletely defined. To better understand early human islet cell development and maturation, we collected 123 ped...

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Hlavní autoři: Diane C. Saunders, Fan Feng, Alexander L. Hopkirk, Kristie I. Aamodt, Nathaniel Hart, Fong Cheng Pan, Conrad V. Reihsmann, Nike Izmaylov, Shaojun Mei, Brandon A. Sherrod, Corey Davis, Nongyao Nonpanya, Yasminye D. Pettway, Keval P. Patel, Kai S. Lee, Jeff Duryea, Rachana Haliyur, Radhika Aramandla, Heather Durai, Greg Poffenberger, Alexandra Martin, Amanda L. Posgai, Irina Kusmartseva, Maria L. Beery, Mingder Yang, Ke Xu, Hakmook Kang, Dale L. Greiner, Leonard D. Shultz, Jean-Philippe Cartailler, Rita Bottino, Mark A. Atkinson, Christopher V. E. Wright, Alvin C. Powers, Marcela Brissova
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-06-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-026-73854-y
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