PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice.
Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma (ATLL), an aggressive malignant proliferation of activated CD4+ T lymphocytes. The viral Tax oncoprotein is critically involved in both HTLV-1-replication and T-cell proliferation, a prerequisite t...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2018-03-01
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| coleção: | PLoS Pathogens |
| Acesso em linha: | http://europepmc.org/articles/PMC5882172?pdf=render |
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