Iron, arginine, and redox metabolism in peripheral blood mononuclear cells distinguishes sickle cell disease and pulmonary hypertension

Abstract Pulmonary hypertension (PH) is a severe vascular complication of sickle cell disease (SCD); yet, not all patients with SCD develop PH, and PH also arises independently. This duality underscores the need to understand their intersecting biology. We integrated metabolomic, proteomic, and elem...

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Autors principals:	Francesca I. Cendali, Christina Lisk, Amy Argabright, Monika Dzieciatkowska, Nishant K. Rana, Delaney Swindle, Daniel Stephenson, Julie McAfee, Natalie Westover, Melissa Lucero, Aneta Gandjeva, Kurt Stenmark, Rubin Tuder, Brian B. Graham, Tim Lahm, Vijaya Karoor, Gemlyn George, Kathryn Hassel, Rachelle Nuss, Pavel Davizon‐Castillio, Paul W. Buehler, Angelo D'Alessandro, David C. Irwin
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-03-01
Col·lecció:	HemaSphere
Accés en línia:	https://doi.org/10.1002/hem3.70318
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