A strategy for adenovirus vector targeting with a secreted single chain antibody.
BACKGROUND:Successful gene therapy will require targeted delivery vectors capable of self-directed localization. In this regard, the use of antibodies or single chain antibody fragments (scFv) in conjunction with adenovirus (Ad) vectors remains an attractive means to achieve cell-specific targeting....
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2009-12-01
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| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC2791226?pdf=render |
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