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Sunitinib-induced endocapillary proliferative glomerulonephritis with IgA2 deposit in addition to thrombotic microangiopathy: a case report

Abstract Background Sunitinib, a multi-targeted tyrosine kinase inhibitor, is used as a second-line therapy for gastrointestinal stromal tumors (GIST) resistant to imatinib. However, its impact on the vascular endothelial growth factor (VEGF) pathway can lead to significant toxicities, including hyp...

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Principais autores: Xin Zhang, Hui Wang, Jian Li, Fude Zhou, Minghui Zhao, Tao Su
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:BMC Nephrology
Fag:
Sunitinib
Vascular endothelial growth factor blockade
Thrombotic microangiopathy
IgA2 deposit
Case report
Online adgang:https://doi.org/10.1186/s12882-024-03732-6
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