Sunitinib-induced endocapillary proliferative glomerulonephritis with IgA2 deposit in addition to thrombotic microangiopathy: a case report

Abstract Background Sunitinib, a multi-targeted tyrosine kinase inhibitor, is used as a second-line therapy for gastrointestinal stromal tumors (GIST) resistant to imatinib. However, its impact on the vascular endothelial growth factor (VEGF) pathway can lead to significant toxicities, including hyp...

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Главные авторы:	Xin Zhang, Hui Wang, Jian Li, Fude Zhou, Minghui Zhao, Tao Su
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2024-08-01
Серии:	BMC Nephrology
Предметы:	Sunitinib Vascular endothelial growth factor blockade Thrombotic microangiopathy IgA2 deposit Case report
Online-ссылка:	https://doi.org/10.1186/s12882-024-03732-6
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