The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma

High‐risk neuroblastomas, often associated with MYCN protooncogene amplification, are addicted to polyamines, small polycations vital for cellular functioning. We have previously shown that neuroblastoma cells increase polyamine uptake when exposed to the polyamine biosynthesis inhibitor difluoromet...

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Egile Nagusiak:	Mujahid Azfar, Weiman Gao, Chris Van den Haute, Lin Xiao, Mawar Karsa, Ruby Pandher, Ayu Karsa, Dayna Spurling, Emma Ronca, Angelika Bongers, Xinyi Guo, Chelsea Mayoh, Youri Fayt, Arthur Schoofs, Mark R. Burns, Steven H. L. Verhelst, Murray D. Norris, Michelle Haber, Peter Vangheluwe, Klaartje Somers
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Wiley 2025-03-01
Saila:	Molecular Oncology
Gaiak:	neuroblastoma DFMO ATP13A3 AMXT 1501 polyamine depletion polyamine transport inhibitor
Sarrera elektronikoa:	https://doi.org/10.1002/1878-0261.13789
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