Inter-assay and Inter-site Performance of Alpha-Synuclein Seed Amplification Assays in Synucleinopathies: A Multicenter 2 × 2 Protocol Comparison

Abstract Introduction The α-synuclein seed amplification assay (synSAA) is a biomarker test for synucleinopathies. Different synSAA conditions have different properties, and some of these conditions enable differentiation between diseases associated with Lewy bodies versus those associated with glia...

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Главные авторы:	Roger Plaza-Clar, Maximilian Weber, Vaibhavi Kadam, Christian Deuschle, Yihua Ma, Carly M. Farris, Luis Concha-Marambio, David Mengel, Marcello Rossi, Angela Mammana, Piero Parchi, Matthis Synofzik, Kathrin Brockmann, Thomas Gasser
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Adis, Springer Healthcare 2026-05-01
Серии:	Neurology and Therapy
Предметы:	α-Synuclein Seed amplification assays Synucleinopathies Parkinson’s disease Dementia with Lewy bodies Multiple systems atrophy
Online-ссылка:	https://doi.org/10.1007/s40120-026-00965-5
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