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Improved Pharmacokinetic Feasibilities of Mirabegron-1,2-Ethanedisulfonic Acid, Mirabegron-1,5-Naphthalenedisulfonic Acid, and Mirabegron-L-Pyroglutamic Acid as Co-Amorphous Dispersions in Rats and Mice

Mirabegron (MBR) is a β<sub>3</sub>-adrenoceptor agonist used for treating overactive bladder syndrome. Due to its poor solubility and low bioavailability (<i>F</i>), the development of novel MBR formulations has garnered increasing attention. Recently, co-amorphous dispersions of MBR, such as MBR-1...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Seo-Yeon Kim, Byung Hoon You, Mingoo Bae, Seung Yon Han, Kiwon Jung, Young Hee Choi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2023-09-01
Rangatū:Pharmaceutics
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1999-4923/15/9/2277
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