Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis

Skin pan-fibrosis diseases—such as hypertrophic scar (HS), keloid scar (KS), and systemic sclerosis (SSc)—pose significant threats to patients' health and quality of life. In this study, the authors conducted both in vivo and in vitro experiments and discovered that the serine/threonine kinase PIM1...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Jianzhang Wang, Yajuan Song, Xiaoying Tan, Tong Wang, Yi Shi, Xingbo Xu, Juan Du, Zhou Yu, Baoqiang Song
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2025-05-01
Sarja:	Redox Biology
Aiheet:	Skin fibrosis Ferroptosis Common biomarkers PIM1 Bruceine D
Linkit:	http://www.sciencedirect.com/science/article/pii/S2213231725001326
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