Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells
Functional annotation of the vast noncoding landscape of the diploid human genome still remains a major challenge of genomic research. Here the authors present a scarless, biallelic, and 100 kb-scale mutagenesis in human cells that uncovers functional significances of endogenous introns and retrotra...
Gardado en:
| Principais autores: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2022-07-01
|
| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-022-31982-1 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|