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Zebrafish startle habituation: How readout choice influences the interpretation of chemical effects in neurotoxicity screening

Zebrafish behavioral profiling is increasingly used in environmentally oriented New Approach Methodologies (NAMs) for chemical hazard assessment, including neuroactive chemicals. However, interpreting acoustic/vibrational startle habituation requires understanding how different quantification strate...

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Autori principali: Karla Colín-García, Niki Tagkalidou, Ouwais Aljabasini, Eva Prats, Carlos Barata, Leobardo Manuel Gómez-Oliván, Demetrio Raldúa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-07-01
Serie:Ecotoxicology and Environmental Safety
Soggetti:
Zebrafish
Eleutheroembryo
Acoustic startle response
Habituation
Behavioral profiling
Environmental neurotoxicity
Accesso online:http://www.sciencedirect.com/science/article/pii/S0147651326006184
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