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Zebrafish startle habituation: How readout choice influences the interpretation of chemical effects in neurotoxicity screening

Zebrafish behavioral profiling is increasingly used in environmentally oriented New Approach Methodologies (NAMs) for chemical hazard assessment, including neuroactive chemicals. However, interpreting acoustic/vibrational startle habituation requires understanding how different quantification strate...

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Principais autores: Karla Colín-García, Niki Tagkalidou, Ouwais Aljabasini, Eva Prats, Carlos Barata, Leobardo Manuel Gómez-Oliván, Demetrio Raldúa
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-07-01
Series:Ecotoxicology and Environmental Safety
Assuntos:
Zebrafish
Eleutheroembryo
Acoustic startle response
Habituation
Behavioral profiling
Environmental neurotoxicity
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0147651326006184
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