Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker

Abstract Background RING finger protein 43 (RNF43), an E3 ubiquitin ligase, is a homologous gene mutated in several cancers. However, the pan-cancer panoramic picture of RNF43 and its predictive value for tumor immune phenotypes and immunotherapeutic efficacy are still largely unclear. Our study aim...

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Hlavní autoři:	Yingting Xu, Zhengjun Lin, Yuqiao Ji, Chen Zhang, Xianzhe Tang, Chuan Li, Tang Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-10-01
Edice:	European Journal of Medical Research
Témata:	RNF43 Pan-cancer Immunotherapeutic efficacy Prognostic biomarker Immune microenvironment Genetic alternations
On-line přístup:	https://doi.org/10.1186/s40001-023-01383-1
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