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Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker

Abstract Background RING finger protein 43 (RNF43), an E3 ubiquitin ligase, is a homologous gene mutated in several cancers. However, the pan-cancer panoramic picture of RNF43 and its predictive value for tumor immune phenotypes and immunotherapeutic efficacy are still largely unclear. Our study aim...

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Principais autores: Yingting Xu, Zhengjun Lin, Yuqiao Ji, Chen Zhang, Xianzhe Tang, Chuan Li, Tang Liu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-10-01
Serier:European Journal of Medical Research
Fag:
RNF43
Pan-cancer
Immunotherapeutic efficacy
Prognostic biomarker
Immune microenvironment
Genetic alternations
Online adgang:https://doi.org/10.1186/s40001-023-01383-1
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