Cimetidine Does Not Inhibit 5-Aminolevulinic Acid Synthase or Heme Oxygenase Activity: Implications for Treatment of Acute Intermittent Porphyria and Erythropoietic Protoporphyria

Acute intermittent porphyria (AIP) is characterized by acute neurovisceral attacks that are precipitated by the induction of hepatic 5-aminolevulinic acid synthase 1 (ALAS1). In erythropoietic protoporphyria (EPP), sun exposure leads to skin photosensitivity due to the overproduction of photoreactiv...

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Bibliografiske detaljer

Principais autores:	Makiko Yasuda, Sangmi Lee, Lin Gan, Hector A. Bergonia, Robert J. Desnick, John D. Phillips
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-12-01
Serier:	Biomolecules
Fag:	porphyrias acute intermittent porphyria erythropoietic protoporphyria disorders of heme biosynthesis therapies for porphyrias cimetidine
Online adgang:	https://www.mdpi.com/2218-273X/14/1/27
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