Determining the Bordetella LPS structural features that influence TLR4 downstream signaling
Upon recognizing bacterial lipopolysaccharide (LPS), human TLR4 initiates two distinct signaling pathways: the MyD88 pathway from the cell surface or the TRIF pathway following endocytosis. While the first is associated with strong pro-inflammatory responses, the latter is linked to dendritic cell m...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2025-02-01
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| Серии: | Frontiers in Microbiology |
| Предметы: | |
| Online-ссылка: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1540534/full |
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