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Metallochaperones regulate intracellular copper levels.

Copper (Cu) is an important enzyme co-factor that is also extremely toxic at high intracellular concentrations, making active efflux mechanisms essential for preventing Cu accumulation. Here, we have investigated the mechanistic role of metallochaperones in regulating Cu efflux. We have constructed...

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Detalhes bibliográficos
Principais autores: W Lee Pang, Amardeep Kaur, Alexander V Ratushny, Aleksandar Cvetkovic, Sunil Kumar, Min Pan, Adam P Arkin, John D Aitchison, Michael W W Adams, Nitin S Baliga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC3551603?pdf=render
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