Local translatome sustains synaptic function in impaired Wallerian degeneration

Abstract After injury, severed axons separated from their somas activate programmed axon degeneration, a conserved pathway to initiate their degeneration within a day. Conversely, severed projections deficient in programmed axon degeneration remain morphologically preserved with functional synapses...

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Podrobná bibliografie

Hlavní autoři:	Maria Paglione, Leonardo Restivo, Sarah Zakhia, Arnau Llobet Rosell, Marco Terenzio, Lukas J Neukomm
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer Nature 2024-10-01
Edice:	EMBO Reports
Témata:	Wallerian Degeneration Programmed Axon Degeneration Local mRNA Translation Synaptic Function Antennal Grooming Behavior
On-line přístup:	https://doi.org/10.1038/s44319-024-00301-8
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