A Broad-Spectrum Antiviral Molecule, Protoporphyrin IX, Acts as a Moderator of HIV-1 Capsid Assembly by Targeting the Capsid Hexamer
ABSTRACT The capsid protein (CA), an essential component of human immunodeficiency virus type 1 (HIV-1), represents an appealing target for antivirals. Small molecules targeting the CAI-binding cavity in the C-terminal domain of HIV-1 CA (CA CTD) confer potent antiviral activities. In this study, we...
Guardat en:
| Autors principals: | , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2023-02-01
|
| Col·lecció: | Microbiology Spectrum |
| Matèries: | |
| Accés en línia: | https://journals.asm.org/doi/10.1128/spectrum.02663-22 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|