Loop engineering improves prime editing efficiency
Prime editor (PE) offers significant translational potential due to its diverse editing outcomes. However, its editing efficiency is generally lower than that of wild-type Cas9 and base editor (BE). Previous investigations have suggested that the availability of the primer binding site (PBS) and rev...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2025-12-01
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| Edice: | Molecular Therapy: Nucleic Acids |
| Témata: | |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S216225312500318X |
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