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Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer

Abstract Urokinase-type plasminogen activator receptor (uPAR) is an attractive target for the treatment of cancer, because it is expressed at low levels in healthy tissues but at high levels in malignant tumours. uPAR is closely related to the invasion and metastasis of malignant tumours, plays impo...

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Asıl Yazarlar: Bing-Tao Zhai, Huan Tian, Jing Sun, Jun-Bo Zou, Xiao-Fei Zhang, Jiang-Xue Cheng, Ya-Jun Shi, Yu Fan, Dong-Yan Guo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2022-03-01
Seri Bilgileri:Journal of Translational Medicine
Konular:
Urokinase-type plasminogen activator receptor (uPAR)
Nanoparticles (NPs)
Photodynamic therapy (PDT)/photothermal therapy (PTT)
Oncolytic virotherapy
Gene therapy technologies
Monoclonal antibody therapy
Online Erişim:https://doi.org/10.1186/s12967-022-03329-3
Etiketler: Etiketle
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