Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer

Abstract Urokinase-type plasminogen activator receptor (uPAR) is an attractive target for the treatment of cancer, because it is expressed at low levels in healthy tissues but at high levels in malignant tumours. uPAR is closely related to the invasion and metastasis of malignant tumours, plays impo...

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Principais autores:	Bing-Tao Zhai, Huan Tian, Jing Sun, Jun-Bo Zou, Xiao-Fei Zhang, Jiang-Xue Cheng, Ya-Jun Shi, Yu Fan, Dong-Yan Guo
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2022-03-01
Series:	Journal of Translational Medicine
Assuntos:	Urokinase-type plasminogen activator receptor (uPAR) Nanoparticles (NPs) Photodynamic therapy (PDT)/photothermal therapy (PTT) Oncolytic virotherapy Gene therapy technologies Monoclonal antibody therapy
Acceso en liña:	https://doi.org/10.1186/s12967-022-03329-3
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