Tolerance to the Antinociceptive Effects of Chronic Morphine Requires C-Jun N-Terminal Kinase
Background Morphine and fentanyl are opioid analgesics in wide clinical use that act through the μ-opioid receptor (MOR). However, one limitation of their long-term effectiveness is the development of tolerance. Receptor desensitization has been proposed as a putative mechanism driving tolerance to...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
SAGE Publishing
2015-06-01
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| Cyfres: | Molecular Pain |
| Mynediad Ar-lein: | https://doi.org/10.1186/s12990-015-0031-4 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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