Tolerance to the Antinociceptive Effects of Chronic Morphine Requires C-Jun N-Terminal Kinase
Background Morphine and fentanyl are opioid analgesics in wide clinical use that act through the μ-opioid receptor (MOR). However, one limitation of their long-term effectiveness is the development of tolerance. Receptor desensitization has been proposed as a putative mechanism driving tolerance to...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
SAGE Publishing
2015-06-01
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| Saila: | Molecular Pain |
| Sarrera elektronikoa: | https://doi.org/10.1186/s12990-015-0031-4 |
| Etiketak: |
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