Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

Abstract Background Sarcospan (SSPN) is a transmembrane protein that interacts with the sarcoglycans (SGs) to form a tight subcomplex within the dystrophin-glycoprotein complex that spans the sarcolemma and interacts with laminin in the extracellular matrix. Overexpression of SSPN ameliorates Duchen...

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Principais autores:	Angela K. Peter, Gaynor Miller, Joana Capote, Marino DiFranco, Alhondra Solares-Pérez, Emily L. Wang, Jim Heighway, Ramón M. Coral-Vázquez, Julio Vergara, Rachelle H. Crosbie-Watson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-06-01
coleção:	Skeletal Muscle
Assuntos:	Duchenne muscular dystrophy Dystrophin Limb girdle muscular dystrophy Microspan Nanospan Sarcolemma
Acesso em linha:	http://link.springer.com/article/10.1186/s13395-017-0127-9
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