Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer

Alternative splicing (AS) plays an important role in gene regulation, and AS perturbations are frequently observed in cancer. RNA binding protein (RBP) is one of the molecular determinants of AS, and perturbations in RBP-gene network activity are causally associated with cancer development. Here, we...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Junyi Li, Tao Pan, Liuxin Chen, Qi Wang, Zhenghong Chang, Weiwei Zhou, Xinhui Li, Gang Xu, Xia Li, Yongsheng Li, Yunpeng Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2021-06-01
Serie:	Molecular Therapy: Nucleic Acids
Soggetti:	RNA binding protein alterative splicing regulatory network cancer therapeutic targets
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2162253121000998
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!