Selection of biophysically favorable antibody variants using a modified Flp-In CHO mammalian display platform
Mammalian display enables the selection of biophysically favorable antibodies from a large IgG antibody library displayed on the plasma membrane of mammalian cells. We constructed and validated a novel mammalian display platform utilizing the commercially available Flp-In CHO cell line as a starting...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2023-05-01
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| coleção: | Frontiers in Bioengineering and Biotechnology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1170081/full |
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