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Carbapenem-resistant Enterobacterales (CRE) acquisition and molecular characterization following colistin monotherapy and colistin-meropenem combination therapy: findings from the AIDA randomized trial

Abstract Background Colistin-carbapenem combination therapy is frequently used for carbapenem-resistant Gram-negative infections, but its impact on subsequent acquisition of carbapenem-resistant Enterobacterales (CRE) requires further investigation. We evaluated the incidence of CRE acquisition and...

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Hlavní autoři: Amir Nutman, Elizabeth Temkin, Jonathan Lellouche, Maayan Amar Ben Dalak, Ella Kaplan, Mor Lurie-Weinberger, Yael Dishon Benattar, Ami Neuberger, Anat Stern, Vered Daitch, Noa Eliakim-Raz, Emanuele Durante-Mangoni, Mariano Bernardo, Domenico Iossa, George Daikos, Anna Skiada, Ioannis Pavleas, Lena Friberg, Ursula Theuretzbacher, Leonard Leibovici, Mical Paul, Yehuda Carmeli, AIDA Study Group
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-11-01
Edice:Antimicrobial Resistance and Infection Control
Témata:
Colistin
Meropenem
Combination treatment
Infection
Colonization
Carbapenem-resistant Enterobacterales (CRE)
On-line přístup:https://doi.org/10.1186/s13756-025-01651-1
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