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Prevalence and Clinical Consequences of Colistin Heteroresistance and Evolution into Full Resistance in Carbapenem-Resistant Acinetobacter baumannii

ABSTRACT Colistin heteroresistance (HR) refers to a bacterial population comprised of several subpopulations with different levels of resistance to colistin. In this study, we discuss the classic form of HR, in which a resistant subpopulation exists within a predominantly susceptible population. We...

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Principais autores: Hadas Kon, Amichay Hameir, Amir Nutman, Elizabeth Temkin, Alona Keren Paz, Jonathan Lellouche, David Schwartz, David S. Weiss, Keith S. Kaye, George L. Daikos, Anna Skiada, Emanuele Durante-Mangoni, Yael Dishon Benattar, Dafna Yahav, Vered Daitch, Mariano Bernardo, Domenico Iossa, Lena E. Friberg, Ursula Theuretzbacher, Leonard Leibovici, Yaakov Dickstein, Dina Pollak, Sigal Mendelsohn, Mical Paul, Yehuda Carmeli
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2023-06-01
Serier:Microbiology Spectrum
Fag:
Acinetobacter baumannii
carbapenem-resistance
colistin
heteroresistance
population analysis profiling
Online adgang:https://journals.asm.org/doi/10.1128/spectrum.05093-22
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